Université Lille 2 Droit et Santé

Dimanche 29 novembre 2020
Université Lille 2
Service de la Recherche, de la Valorisation et de l'Information Scientifique (SeRVIS)
42, rue Paul Duez
59000 - Lille - France
TĂ©l. : +33 (0)3 20 96 52 20
Fax : +33 (0)3 20 96 43 38

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Récepteurs nucléaires, maladies cardiovasculaires et diabète

Mise Ă  jour 2015 en cours



Institut Pasteur de Lille
1, rue du Pr Calmette
BP 245
59019 Lille CĂ©dex

TĂ©l. : +33 (0)3 20 87 78 25 / 77 52

Fax : +33 (0)3 20 87 73 60

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Principales publications de ces 5 dernières années extraites de SAMPRA

Delsart P, Maldonado-Kauffmann P, Bic M, Boudghene-Stambouli F, Sobocinski J, Juthier F & al , Post aortic dissection: Gap between activity recommendation and real life patients aerobic capacities.Int. J. Cardiol., 2016 , 271-276

Charpentier A, Lebreton A, Rauch A, Bauters A, Trillot N, Nibourel O & al , Microparticles phenotypes are associated with driver mutations and distinct thrombotic risks in Essential Thrombocythaemia.Haematologica, 2016

Hennuyer N, Duplan I, Paquet C, Vanhoutte J, Woitrain E, Touche V & al , The novel selective PPAR? modulator (SPPARM?) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.Atherosclerosis, 2016

Ducloy-Bouthors AS, Duhamel A, Kipnis E, Tournoys A, Prado-Dupont A, Elkalioubie A & al , Postpartum haemorrhage related early increase in D-dimers is inhibited by tranexamic acid: haemostasis parameters of a randomized controlled open labelled trial.Br J Anaesth, 2016 , 641-8

Spinelli V, Lalloyer F, Baud G, Osto E, Kouach M, Daoudi M & al , Influence of Roux-en-Y gastric bypass on plasma bile acid profiles: a comparative study between rats, pigs and humans.Int J Obes (Lond), 2016

Julia V, Staumont-Salle D, Dombrowicz D , [Role of fractalkine/CX3CL1 and its receptor CX3CR1 in allergic diseases].Med Sci (Paris), 2016 , 260-6

Veyradier A, Boisseau P, Fressinaud E, Caron C, Ternisien C, Giraud M & al , A Laboratory Phenotype/Genotype Correlation of 1167 French Patients From 670 Families With von Willebrand Disease: A New Epidemiologic Picture.Medicine (Baltimore), 2016 , e3038

Rauch A, Caron C, Vincent F, Jeanpierre E, Ternisien C, Boisseau P & al , A novel ELISA-based diagnosis of acquired von Willebrand disease with increased VWF proteolysis.Thromb. Haemost., 2016 , 950-9

Rousse N, Robin E, Juthier F, Hysi I, Banfi C, Al Ibrahim M & al , Extracorporeal Life Support in Out-of-Hospital Refractory Cardiac Arrest.,Artif Organs, 2015

Haas JT, Francque S, Staels B , Pathophysiology and Mechanisms of Nonalcoholic Fatty Liver Disease.Annu. Rev. Physiol., 2016 , 181-205

Briand O, Touche V, Colin S, Brufau G, Davalos A, Schonewille M & al , Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1Gastroenterology, 2016 , 650-658

Dubois V, Laurent MR, Jardi F, Antonio L, Lemaire K, Goyvaerts L & al , Androgen Deficiency Exacerbates High-Fat Diet-Induced Metabolic Alterations in Male MiceEndocrinology, 2016 , 648-665

Sottejeau Y, Bretteville A, Cantrelle FX, Malmanche N, Demiaute F, Mendes T & al , Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domainActa Neuropathol. Commun., 2015

Dubois V, Simitsidellis I, Laurent MR, Jardi F, Saunders PTK, Vanderschueren D & al , Enobosarm (GTx-024) Modulates Adult Skeletal Muscle Mass Independently of the Androgen Receptor in the Satellite Cell LineageEndocrinology, 2015 , 4522-4533

Elkalioubie A, Haulon S, Duhamel A, Rosa M, Rauch A, Staels B & al , Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery DiseaseAm. J. Cardiol., 2015 , 1451-1456

Salmon C, Barriat S, Demanez L, Magis D, Lefebvre P , Audiometric Results after Stapedotomy Operations in Patients with Otosclerosis and Preoperative Small Air-Bone GapsAudiol. Neuro-Otol., 2015 , 330-336

Mouquet F, Bouabdallaoui N , Peripartum cardiomyopathyPresse Med., 2015 , 798-804

Trabelsi MS, Daoudi M, Prawitt J, Ducastel S, Touche V, Sayin SI & al , Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cellsNat. Commun., 2015

Spinelli V, Martin C, Dorchies E, Vallez E, Dehondt H, Trabelsi MS & al , Screening strategy to generate cell specific recombination: a case report with the RIP-Cre miceTransgenic Res., 2015 , 803-812

Pawlak M, BaugĂ© E, Lalloyer F, Lefebvre P, Staels B , Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Ppar alpha DeficiencyMol. Endocrinol., 2015 , 1134-1143

Tailleux A, Staels B , Overview of the Measurement of Lipids and Lipoproteins in Mice.Curr Protoc Mouse Biol, 2011 , 265-77

Robin E, Futier E, Pires O, Fleyfel M, Tavernier B, Lebuffe G & al , Central venous-to-arterial carbon dioxide difference as a prognostic tool in high-risk surgical patientsCrit. Care, 2015

Roma-Lavisse C, Tagzirt M, Zawadzki C, Lorenzi R, Vincentelli A, Haulon S & al , M1 and M2 macrophage proteolytic and angiogenic profile analysis in atherosclerotic patients reveals a distinctive profile in type 2 diabetesDiabetes Vasc. Dis. Res., 2015 , 279-289

Rousse N, Juthier F, Pincon C, Hysi I, Banfi C, Robin E & al , ECMO as a bridge to decision: Recovery, VAD, or heart transplantation?Int. J. Cardiol., 2015 , 620-627

Bauduer F, de Raucourt E, Boyer-Neumann C, Trossaert M, Beurrier P, Faradji A & al , Factor XI replacement for inherited factor XI deficiency in routine clinical practice: results of the HEMOLEVEN prospective 3-year postmarketing studyHaemophilia, 2015 , 481-489

Hysi I, Juthier F, Fabre O, Fouquet O, Rousse N, Banfi C & al , Aortic root surgery improves long-term survival after acute type A aortic dissectionInt. J. Cardiol., 2015 , 285-290

Francque S, Verrijken A, Caron S, Prawitt J, Paumelle R, Derudas B & al , PPAR alpha gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitisJ. Hepatol., 2015 , 164-173

Van Belle E, Rauch A, Vincentelli A, Jeanpierre E, Legendre P, Juthier F & al , von Willebrand Factor as a Biological Sensor of Blood Flow to Monitor Percutaneous Aortic Valve InterventionsCirc.Res., 2015 , 1193-1201

Mouquet F, Jourdain M, Desprez P, Auffray JL, Ennezat PV , Chlamydia infection: An uncommon cause of sexually transmitted myopericarditis,Rev. Med. Interne, 2015 , 777-779

Chinetti-Gbaguidi G, Copin C, Derudas B, Vanhoutte J, Zawadzki C, Jude B & al , The coronary artery disease-associated gene C6ORF105 is expressed in human macrophages under the transcriptional control of PPAR gammaFEBS Lett., 2015 , 461-466

Dubois-Chevalier J, Staels B, Lefebvre P, Eeckhoute J , The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiationNucleus, 2015 , 15-18

Hanf R, Millatt LJ, Cariou B, Noel B, Rigou G, Delataille P & al , The dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 exerts anti-diabetic effects in db/db mice without peroxisome proliferator-activated receptor gamma-associated adverse cardiac effects,Diabetes Vasc. Dis. Res., 2014 , 440-447

Dubois-Chevalier J, Oger F, Dehondt H, Firmin FF, Gheeraert C, Staels B & al , A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiationNucleic Acids Res., 2014 , 10943-10959

Marciniak C, Marechal X, Montaigne D, Neviere R, Lancel S , Cardiac contractile function and mitochondrial respiration in diabetes-related mouse modelsCardiovasc. Diabetol., 2014

Pawlak M, Bauge E, Bourguet W, De Bosscher K, Lalloyer F, Tailleux A & al , The Transrepressive Activity of Peroxisome Proliferator-Activated Receptor Alpha Is Necessary and Sufficient to Prevent Liver Fibrosis in MiceHepatology, 2014 , 1593-1606

Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G & al , Myocardial Contractile Dysfunction Is Associated With Impaired Mitochondrial Function and Dynamics in Type 2 Diabetic but Not in Obese PatientsCirculation, 2014 , 554-+

Staumont-Salle D, Fleury S, Lazzari A, Molendi-Coste O, Hornez N, Lavogiez C & al , CX(3)CL1 (fractalkine) and its receptor CX(3)CR1 regulate atopic dermatitis by controlling effector T cell retention in inflamed skinJ. Exp. Med., 2014 , 1185-1196

Bantubungi K, Hannou SA, Caron-Houde S, Vallez E, Baron M, Lucas A & al , Cdkn2a/p16(Ink4a) Regulates Fasting-Induced Hepatic Gluconeogenesis Through the PKA-CREB-PGC1 alpha PathwayDiabetes, 2014 , 3199-3209

Legry V, Van Rooyent DM, Lambert B, Sempoux C, Poekes L, Espanol-Suner R & al , Endoplasmic reticulum stress does not contribute to steatohepatitis in obese and insulin-resistant high-fat-diet-fed foz/foz miceClin. Sci., 2014 , 507-518

Oger F, Gheeraert C, Mogilenko D, Benomar Y, Molendi-Coste O, Bouchaert E & al , Cell-Specific Dysregulation of MicroRNA Expression in Obese White Adipose TissueJ. Clin. Endocrinol. Metab., 2014 , 2821-2833

Lien F, Berthier A, Bouchaert E, Gheeraert C, Alexandre J, Porez G & al , Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalkJ. Clin. Invest., 2014 , 1037-1051

Mazuy C, Ploton M, Eeckhoute J, Berrabah W, Staels B, Lefebvre P & al , Palmitate increases Nur77 expression by modulating ZBP89 and Sp1 binding to the Nur77 proximal promoter in pancreatic ?-cells.FEBS Lett., 2013

Mazuy C, Ploton M, Eeckhoute J, Berrabah W, Staels B, Lefebvre P & al , Palmitate increases Nur77 expression by modulating ZBP89 and Sp1 binding to the Nur77 proximal promoter in pancreatic beta-cellsFEBS Lett., 2013 , 3883-3890

Oger F, Dubois-Chevalier J, Gheeraert C, Avner S, Durand E, Froguel P & al , Peroxisome Proliferator-activated Receptor gamma Regulates Genes Involved in Insulin/Insulin-like Growth Factor Signaling and Lipid Metabolism during Adipogenesis through Functionally Distinct Enhancer ClassesJ. Biol. Chem., 2014 , 708-722

Berrabah W, Aumercier P, Gheeraert C, Dehondt H, Bouchaert E, Alexandre J & al , Glucose Sensing O-GlcNAcylation Pathway Regulates the Nuclear Bile Acid Receptor Farnesoid X Receptor (FXR)Hepatology, 2014 , 2022-2033

Porez G, Gross B, Prawitt J, Gheeraert C, Berrabah W, Alexandre J & al , The Hepatic Orosomucoid/alpha 1-Acid Glycoprotein Gene Cluster Is Regulated by the Nuclear Bile Acid Receptor FXREndocrinology, 2013 , 3690-3701

Woldt E, Sebti Y, Solt LA, Duhem C, Lancel S, Eeckhoute J & al , Rev-erb-alpha modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagyNat. Med., 2013 , 1039-+

Dombrowicz D , Associate editor David Dombrowicz.Int. Arch. Allergy Immunol., 2013 , 5

Flajollet S, Rachez C, Ploton M, Schulz C, Gallais R, Metivier R & al , The Elongation Complex Components BRD4 and MLLT3/AF9 Are Transcriptional Coactivators of Nuclear Retinoid ReceptorsPLoS One, 2013

Staels B, Rubenstrunk A, Noel B, Rigou G, Delataille P, Millatt LJ & al , Hepatoprotective Effects of the Dual Peroxisome Proliferator-Activated Receptor Alpha/Delta Agonist, GFT505, in Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis,Hepatology, 2013 , 1941-1952

Palud A, Marciniak C, Montaigne D, Marechal X, Ballot C, Hassoun SM & al , Macrophage Migration Inhibitory Factor Inhibition Is Deleterious for High-Fat Diet-Induced Cardiac DysfunctionPLoS One, 2013

Caron S, Samanez CH, Dehondt H, Ploton M, Briand O, Lien F & al , Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human HepatocytesMol. Cell. Biol., 2013 , 2202-2211

Glineur C, Gross B, Neve B, Rommens C, Chew GT, Martin-Nizard F & al , Fenofibrate Inhibits Endothelin-1 Expression by Peroxisome Proliferator-Activated Receptor alpha-Dependent and Independent Mechanisms in Human Endothelial CellsArterioscler. Thromb. Vasc. Biol., 2013 , 621-+

Lancel S, Montaigne D, Marechal X, Marciniak C, Hassoun SM, Decoster B & al , Carbon Monoxide Improves Cardiac Function and Mitochondrial Population Quality in a Mouse Model of Metabolic SyndromePLoS One, 2012

Colin S, Briand O, Touche V, Wouters K, Baron M, Pattou F & al , Activation of intestinal peroxisome proliferator-activated receptor- increases high-density lipoprotein productionEur. Heart J., 2013 , 2566-+

Samanez CH, Caron S, Briand O, Dehondt H, Duplan I, Kuipers F & al , The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolismArch. Physiol. Biochem., 2012 , 102-111

Wouters K, Cudejko C, Gijbels MJJ, Fuentes L, Bantubungi K, Vanhoutte J & al , Bone Marrow p16(INK4a)-Deficiency Does Not Modulate Obesity, Glucose Homeostasis or Atherosclerosis DevelopmentPLoS One, 2012

Berthier A, Oger F, Gheeraert C, Boulahtou A, Le Guevel R, Balaguer P & al , The Novel Antibacterial Compound Walrycin A Induces Human PXR Transcriptional ActivityToxicol. Sci., 2012 , 225-235

Briand O, Helleboid-Chapman A, Ploton M, Hennuyer N, Carpentier R, Pattou F & al , The Nuclear Orphan Receptor Nur77 Is a Lipotoxicity Sensor Regulating Glucose-Induced Insulin Secretion in Pancreatic beta-CellsMol. Endocrinol., 2012 , 399-413

Chinetti-Gbaguidi G, Bouhlel MA, Copin C, Duhem C, Derudas B, Neve B & al , Peroxisome Proliferator-Activated Receptor-gamma Activation Induces 11 beta-Hydroxysteroid Dehydrogenase Type 1 Activity in Human Alternative MacrophagesArterioscler. Thromb. Vasc. Biol., 2012 , 677-U342

Duez H, Cariou B, Staels B , DPP-4 inhibitors in the treatment of type 2 diabetesBiochem. Pharmacol., 2012 , 823-832

Fuentes L, Wouters K, Hannou SA, Cudejko C, Rigamonti E, Mayi TH & al , Downregulation of the tumour suppressor p16(INK4A) contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotypeDiabetologia, 2011 , 3150-3156

Barriat S, van Wijck F, Staecker H, Lefebvre PP , Intratympanic Steroid Therapy Using the Silverstein Microwick (TM) for Refractory Sudden Sensorineural Hearing Loss Increases Speech IntelligibilityAudiol. Neuro-Otol., 2012 , 105-111

Cudejko C, Wouters K, Fuentes L, Hannou SA, Paquet C, Bantubungi K & al , p16(INK4a) deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophagesBlood, 2011 , 2556-2566

Prawitt J, Abdelkarim M, Stroeve JHM, Popescu I, Duez H, Velagapudi VR & al , Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of ObesityDiabetes, 2011 , 1861-1871

Baron M, Leroyer AS, Majd Z, Lalloyer F, Vallez E, Bantubungi K & al , PPAR alpha activation differently affects microparticle content in atherosclerotic lesions and liver of a mouse model of atherosclerosis and NASHAtherosclerosis, 2011 , 69-76

Berthier A, Elie-Caille C, Lesniewska E, Delage-Mourroux R, Boireau W , Label-free sensing and atomic force spectroscopy for the characterization of protein-DNA and protein-protein interactions: application to estrogen receptorsJ. Mol. Recognit., 2011 , 429-435

Lalloyer F, Wouters K, Baron M, Caron S, Vallez E, Vanhoutte J & al , Peroxisome Proliferator-Activated Receptor-alpha Gene Level Differently Affects Lipid Metabolism and Inflammation in Apolipoprotein E2 Knock-In MiceArterioscler. Thromb. Vasc. Biol., 2011 , 1573-U198

Prawitt J, Caron S, Staels B , Bile Acid Metabolism and the Pathogenesis of Type 2 DiabetesCurr. Diabetes Rep., 2011 , 160-166

Gross B, Hennuyer N, Bouchaert E, Rommens C, Grillot D, Mezdour H & al , Generation and characterization of a humanized PPAR delta mouse modelBr. J. Pharmacol., 2011 , 192-208

Chinetti-Gbaguidi G, Baron M, Bouhlel MA, Vanhoutte J, Copin C, Sebti Y & al , Human Atherosclerotic Plaque Alternative Macrophages Display Low Cholesterol Handling but High Phagocytosis Because of Distinct Activities of the PPAR gamma and LXR alpha Pathways,Circ.Res., 2011 , 985-995

Daoudi M, Hennuyer N, Borland MG, Touche V, Duhem C, Gross B & al , PPAR beta/delta Activation Induces Enteroendocrine L Cell GLP-1 ProductionGastroenterology, 2011 , 1564-1574

Serandour AA, Avner S, Percevault F, Demay F, Bizot M, Lucchetti-Miganeh C & al , Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancersGenome Res., 2011 , 555-565

Caron S, Verrijken A, Mertens I, Samanez CH, Mautino G, Haas JT & al , Transcriptional Activation of Apolipoprotein CIII Expression by Glucose May Contribute to Diabetic DyslipidemiaArterioscler. Thromb. Vasc. Biol., 2011 , 513-519

Prawitt J, Staels B , Bile Acid Sequestrants: Glucose-Lowering MechanismsMetab. Syndr. Relat. Disord., 2010 , S3-S8

Abdelkarim M, Caron S, Duhem C, Prawitt J, Dumont J, Lucas A & al , The Farnesoid X Receptor Regulates Adipocyte Differentiation and Function by Promoting Peroxisome Proliferator-activated Receptor-gamma and Interfering with the Wnt/beta-Catenin PathwaysJ. Biol. Chem., 2010 , 36759-36767

Duez H, Staels B , Nuclear Receptors Linking Circadian Rhythms and Cardiometabolic ControlArterioscler. Thromb. Vasc. Biol., 2010 , 1529-1534

Popescu IR, Helleboid-Chapman A, Lucas A, Vandewalle B, Dumont J, Bouchaert E & al , The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicityFEBS Lett., 2010 , 2845-2851

Staels B, Handelsman Y, Fonseca V , Bile Acid Sequestrants for Lipid and Glucose ControlCurr. Diabetes Rep., 2010 , 70-77

Fonseca VA, Handelsman Y, Staels B , Colesevelam lowers glucose and lipid levels in type 2 diabetes: the clinical evidenceDiabetes Obes. Metab., 2010 , 384-392

Lalloyer F, Staels B , Fibrates, Glitazones, and Peroxisome Proliferator-Activated ReceptorsArterioscler. Thromb. Vasc. Biol., 2010 , 894-899

Lefebvre B, Benomar Y, Guedin A, Langlois A, Hennuyer N, Dumont J & al , Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPAR gamma in obese mice and humansJ. Clin. Invest., 2010 , 1454-1468

Berthier A, Seguin S, Sasco AJ, Bobin JY, De Laroche G, Datchary J & al , High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancerBr. J. Cancer, 2010 , 1024-1031

Oger F, Lecorgne A, Sala E, Nardese V, Demay F, Chevance S & al , Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl RingJ. Med. Chem., 2010 , 1937-1950

Finck CL, Harmegnies B, Remacle A, Lefebvre P , Implantation of Esterified Hyaluronic Acid in Microdissected Reinke's Space After Vocal Fold Microsurgery: Short- and Long-Term ResultsJ. Voice, 2010 , 626-635

Duez H , Circadian rhythms and metabolic healthCorresp. M H D N, 2014 , 208-211

Lefebvre P , Organising deliberate innovation in knowledge clusters: from accidental brokering to purposeful brokering processesInt. J. Technol. Manage., 2013 , 212-243

Delhon C, Bernigaud N, Berger JF, Salvador PG, Thiebault S, Ploton M , Evolution and management of humid landscapes in northern Dauphine (Rhone valley, France): Contribution of charcoal and wood studiesHolocene, 2013 , 1447-1465

Hennuyer N, Duplan I, Paquet C, Vanhoutte J, Woitrain E, Touche V & al , The novel selective PPAR alpha modulator (SPPARM alpha) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosisAtherosclerosis, 2016 , 200-208